Anti-RANKL therapy for inflammatory bone
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Allen P. Anandarajah; Edward M. Schwarz
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Article
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2006
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John Wiley and Sons
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English
β 133 KB
## Abstract Focal bone loss around inflamed joints in patients with autoimmune disease, such as rheumatoid arthritis, remains a serious clinical problem. The recent elucidation of the RANK/RANKβligand/OPG pathway and its role as the final effector of osteoclastogenesis and bone resorption has broug