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Anti-proliferative effects of phosphodiester oligodeoxynucleotides

✍ Scribed by Jan L. Bjersing; Andrej Tarkowski; L. Vincent Collins

Book ID
116569027
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
251 KB
Volume
209
Category
Article
ISSN
0171-2985

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## Abstract We have targeted the urokinase‐type plasminogen activator receptor (uPAR) with phosphorothioate antisense oligonucleotides (aODN) __in vitro__ to evaluate the anti‐invasive and anti‐proliferative effects of uPAR down‐regulation, as well as __in vivo__ to evaluate anti‐tumor and anti‐met