✦ LIBER ✦

Anti-PCSK9 Antibody Effectively Lowers Cholesterol in Patients With Statin Intolerance

✍ Scribed by Stroes, Erik; Colquhoun, David; Sullivan, David; Civeira, Fernando; Rosenson, Robert S.; Watts, Gerald F.; Bruckert, Eric; Cho, Leslie; Dent, Ricardo; Knusel, Beat; Xue, Allen; Scott, Rob; Wasserman, Scott M.; Rocco, Michael

Book ID: 122183693
Publisher: Elsevier Science
Year: 2014
Tongue: English
Weight: 196 KB
Volume: 63
Category: Article
ISSN: 1558-3597
DOI: 10.1016/j.jacc.2014.03.019

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Effect of a Monoclonal Antibody to PCSK9

Effect of a Monoclonal Antibody to PCSK9 on Low-Density Lipoprotein Cholesterol Levels in Statin-Intolerant Patients

✍ Sullivan, David; Olsson, Anders G.; Scott, Rob; Kim, Jae B.; Xue, Allen; Gebski, 📂 Article 📅 2012 🏛 American Medical Association 🌐 English ⚖ 290 KB

Effect of a Monoclonal Antibody to PCSK9

Effect of a Monoclonal Antibody to PCSK9 on Low-Density Lipoprotein Cholesterol Levels in Statin-Intolerant Patients

✍ Sullivan, David; Olsson, Anders G.; Scott, Rob; Kim, Jae B.; Xue, Allen; Gebski, 📂 Article 📅 2012 🏛 American Medical Association 🌐 English ⚖ 290 KB

## Context: An estimated 10% to 20% of patients cannot tolerate statins or adequate doses to achieve treatment goals. plasma proprotein convertase subtilisin/kexin type 9 (pcsk9) binds to low-density lipoprotein (ldl) receptors, promoting their degradation and increasing ldl cholesterol levels. in

ETC-1002 Lowers LDL-Cholesterol and is W

ETC-1002 Lowers LDL-Cholesterol and is Well Tolerated in Hypercholesterolemic Patients with Statin Intolerance†

✍ Newton, Roger S.; Thompson, Paul Davis; MacDougall, Diane Elaine; Margulies, Jan 📂 Article 📅 2014 🏛 Elsevier 🌐 English ⚖ 67 KB

Leucine 10 allelic variant in signal pep

Leucine 10 allelic variant in signal peptide of PCSK9 increases the LDL cholesterol-lowering effect of statins in patients with familial hypercholesterolaemia

✍ L. Pisciotta; R. Sallo; C. Rabacchi; A. Wunsch; S. Calandra; S. Bertolini 📂 Article 📅 2012 🏛 Elsevier Science 🌐 English ⚖ 130 KB

Inverse relationship between LDL cholest

Inverse relationship between LDL cholesterol and PCSK9 plasma levels in dyslipidemic cynomolgus monkeys: Effects of LDL lowering by ezetimibe in the absence of statins

✍ Hentze, Hannes; Jensen, Kristian K.; Chia, Ser Mien; Johns, Douglas G.; Shaw, Ra 📂 Article 📅 2013 🏛 Elsevier Science 🌐 English ⚖ 228 KB

Simvastatin (MK-733) effectively lowers

Simvastatin (MK-733) effectively lowers total and low density lipoprotein (LDL)-cholesterol in patients with resistant familial hypercholesterolaemia

✍ N.J. Lewis-Barned; M.J. Ball; J.I. Mann 📂 Article 📅 1988 🏛 Elsevier Science 🌐 English ⚖ 162 KB