Procainamide-induced agranulocytosis wit
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John C. Nelson; John D. Lutton; Arthur E. Fass
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Article
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1984
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John Wiley and Sons
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English
⚖ 440 KB
👁 2 views
A 56-year-old man developed procainamide-induced agranulocytosis. Bone marrow aspiration showed the absence of myeloid elements beyond the promyelocyte stage. Procainamide at therapeutic concentrations in vitro depressed bone marrow granulocyte-macrophage colonies (CFUc) while CFUc growth was normal