๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Anti-inflammatory potency of FR167653, a p38 mitogen-activated protein kinase inhibitor, in mouse models of acute inflammation

โœ Scribed by Tomohiro Nishikori; Kaoru Irie; Taiyo Suganuma; Makoto Ozaki; Toshimasa Yoshioka

Book ID
114015034
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
242 KB
Volume
451
Category
Article
ISSN
0014-2999

No coin nor oath required. For personal study only.

๐Ÿ“œ SIMILAR VOLUMES

Prevention of the onset and progression
Prevention of the onset and progression of collagen-induced arthritis in rats by the potent p38 mitogen-activated protein kinase inhibitor FR167653
โœ Masataka Nishikawa; Akira Myoui; Tetsuya Tomita; Koichiro Takahi; Akihide Nampei ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 488 KB ๐Ÿ‘ 2 views

## Abstract ## Objective FR167653 is a potent inhibitor of p38 mitogenโ€activated protein kinase (MAPK) and inhibits tumor necrosis factor ฮฑ (TNFฮฑ) and interleukinโ€1ฮฒ (ILโ€1ฮฒ) production in inflammatory cells. In this study we investigated the effect of FR167653 on collagenโ€induced arthritis (CIA).

Efficacy of a p38 mitogen activated prot
Efficacy of a p38 mitogen activated protein kinase inhibitor in mitigating an established inflammatory reaction to polyethylene particles in vivo
โœ T. Ma; P.-G. Ren; D. M. Larsen; E. Suenaga; S. Zilber; M. Genovese; R. L. Smith; ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 174 KB

## Abstract The inhibitor of p38 mitogenโ€activated protein kinase (MAPK) is of interest in the nonoperative treatment of periprosthetic osteolysis due to wear particles. Previous studies demonstrated that an oral p38 MAPK inhibitor did not suppress bone formation when given during the initial phase