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Anti-inflammatory drugs and tumor necrosis factor-α production from monocytes: role of transcription factor NF-κB and implication for rheumatoid arthritis therapy

✍ Scribed by Luisa Lavagno; Gabriele Gunella; Claudio Bardelli; Simona Spina; Luigia Grazia Fresu; Ilario Viano; Sandra Brunelleschi


Book ID
113584960
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
340 KB
Volume
501
Category
Article
ISSN
0014-2999

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## Abstract ## Objective To examine the role of interferon regulatory factor 1 (IRF‐1) in tumor necrosis factor α (TNFα)–induced interleukin‐18 binding protein a (IL‐18BPa) expression in rheumatoid arthritis synovial fibroblasts (RASFs). ## Methods TNFα‐induced IRF‐1 expression was assessed by r