## Abstract ## Objective To investigate the roles of MAPKs and NF‐κB in tumor necrosis factor α (TNFα)–induced expression of vascular cell adhesion molecule 1 (VCAM‐1) in human rheumatoid arthritis synovial fibroblasts (RASFs). ## Methods Human RASFs were isolated from synovial tissue obtained f
✦ LIBER ✦
NF-κB–regulated expression of cellular FLIP protects rheumatoid arthritis synovial fibroblasts from tumor necrosis factor α–mediated apoptosis
✍ Scribed by Shaochun Bai; Hongtao Liu; Kun-Hung Chen; Polikseni Eksarko; Harris Perlman; Terry L. Moore; Richard M. Pope
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 307 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0004-3591
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## Abstract ## Objective To examine the role of interferon regulatory factor 1 (IRF‐1) in tumor necrosis factor α (TNFα)–induced interleukin‐18 binding protein a (IL‐18BPa) expression in rheumatoid arthritis synovial fibroblasts (RASFs). ## Methods TNFα‐induced IRF‐1 expression was assessed by r