Anti-immunoglobulins induce death by apoptosis in WEHI-231 B lymphoma cells
✍ Scribed by Laure E. Benhamou; Pierre-andré Cazenave; Pierre Sarthou
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 292 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0014-2980
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
The role of bcl-xL in CD40-mediated rescue from anti-y-induced apoptosis in WEHI-231 B lymphoma cells The phenotypically immature B cell lymphoma WEHI-231 undergoes apoptotic cell death when cultured with anti-immunoglobulin (Ig) antibodies, via a bcl-Zindependent mechanism. We have therefore studi
Engagement of the antigen receptor on murine immature B cells leads to growth arrest followed by apoptosis. Concomitant signaling through CD40 sustains proliferation and rescues the cells from apoptosis. We show here that cross-linking CD40 stimulates the expression of A1, a member of the anti-apopt
## Abstract WEHI‐231 B lymphoma cells have been employed for analysis of antigen‐induced B cell unresponsiveness because these cells undergo cell cycle arrest in G1, accompanied by induction of apoptosis. In the present study, we examined the requirement for toxic small molecules apoptosis‐inducing