Anti-immunoglobulin antibodies induce apoptosis in immature B cell lymphomas
β Scribed by Jhagvaral Hasbold; Gerry G. B. Klaus
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 521 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0014-2980
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Novel panning and screening methodology was devised to isolate high affinity human recombinant scFv antibody fragments with functionally associated properties in B lymphoma cells. The approach was used to generate a panel of apoptosisβinducing antibodies specific for antigens differenti
Mouse malignant T-lymphoma CS-21 cells can survive and proliferate in vitro when co-cultured with CA-I 2 stromal cells isolated from lymph nodes, but CS-2 I cells undergo apoptotic cell death with DNA fragmentation when cultured alone. We immunized rats with CS-2 I cells and raised monoclonal antibo
The role of bcl-xL in CD40-mediated rescue from anti-y-induced apoptosis in WEHI-231 B lymphoma cells The phenotypically immature B cell lymphoma WEHI-231 undergoes apoptotic cell death when cultured with anti-immunoglobulin (Ig) antibodies, via a bcl-Zindependent mechanism. We have therefore studi