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Anti-human Cytomegalovirus Activity by 4′,5,7-Trihydroxy-3′,5′-dimethoxyflavone (TRICIN)

✍ Scribed by Tsugiya Murayama; Yuuzou Tsuchida; Kurumi Yazawa; Rie Yamada; Keiko Matsubara; Hidetaka Sadanari


Book ID
113458348
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
74 KB
Volume
86
Category
Article
ISSN
0166-3542

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Flavonoids are polyphenolic compounds which display a vast array of biological activities and are among the most promising anti-cancer agents. The derivative of quercetin, 5,7,3 0 -trihydroxy-3,4 0 -dimethoxyflavone (THDF), is a natural flavonoid that inhibits cell proliferation and induces apoptosi

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## Abstract Flavonoids are polyphenolic compounds which display a vast array of biological activities and are promising anticancer agents. In this study we investigated the effect of 5,7,3′‐trihydroxy‐3,4′‐dimethoxyflavone (THDF) on viability of nine human tumor cell lines and found that it was hig