Anti-hepatitis C virus E2 (HCV/E2) glycoprotein monoclonal antibodies and neutralization interference
β Scribed by Giuseppe Sautto; Nicasio Mancini; Roberta A. Diotti; Laura Solforosi; Massimo Clementi; Roberto Burioni
- Book ID
- 119190607
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 792 KB
- Volume
- 96
- Category
- Article
- ISSN
- 0166-3542
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract The dynamic features of three specific antiβhepatitis C virus (HCV) antibody subpopulations directed against different conformational epitopes of the viral E2 protein (HCV/E2) have been evaluated in patients with primary and persistent HCV infection; the three subpopulations are present
Active and/or passive immunoprophylaxis against hepatitis C virus (HCV) remain unachieved goals. Monoclonal antibodies might provide one approach to protection. We derived human monoclonal antibodies from the bone marrow of a patient with a well-controlled HCV infection of 22 years duration. Five di