Anti-DNA antibody idiotypes in primary biliary cirrhosis
β Scribed by A. Schattner; Y. Kaburaki; M.M. Kaplan; K.B. Miller
- Book ID
- 113133759
- Publisher
- Elsevier Science
- Year
- 1987
- Tongue
- English
- Weight
- 726 KB
- Volume
- 104
- Category
- Article
- ISSN
- 0008-8749
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Anti-idiotypic antibodies may regulate the immune system and influence pathogenic autoimmunity. We investigated idiotype-anti-idiotype interactions in sera of patients with primary biliary cirrhosis (PBC), normal subjects and animals immunized with pyruvate dehydrogenase complex (PDC) or its derivat
We read with interest the article by Nakamura et al. 1 reporting clinical and prognostic significance of autoantibodies to nuclear pore gp210 antigen and centromere in primary biliary cirrhosis (PBC). By studying 276 Japanese patients, the authors found that anti-gp210 antibody positivity was a risk