Antibody a c t i v i t y t o various histones was examined i n a s o l i d phase radioimmunoassay. More than one h a l f o f the sera from systemic lupus erythematosus (SLE) p a t i e n t s had IgM a c t i v i t y t o t o t a l histones, and a s l i g h t l y lower frequency was observed f o r IgG a
Anti-chromatin and anti-histone antibodies in Egyptian patients with systemic lupus erythematosus
β Scribed by Adel A. Shabana; Atef E. El-Ghawet; Shereen A. Machaly; Ekbal M. Abu Hashim; Basma A. El-Kady; Reham Shaat
- Publisher
- Springer
- Year
- 2009
- Tongue
- English
- Weight
- 145 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0770-3198
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract To investigate the specificity, sensitivity, and concomitant presence of antibodies against histones (H), histone H1 (H1), and histone H3 (H3) in patients with systemic lupus erythematosus (SLE) and analyze their association with SLE. Serum IgG antiβhistones antibodies were detected by
Annexin V has a calcium-dependent binding affinity for anionic phospholipids and activated platelets, and prevents prothrombinase activity. We investigated the clinical significance of IgG anti-annexin V antibodies in patients with SLE. The study population consisted of 140 patients with SLE. Sera w