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Anti-apoptotic effect of transforming growth factor-β1 on human articular chondrocytes: role of protein phosphatase 2A

✍ Scribed by M. Lires-Deán; B. Caramés; B. Cillero-Pastor; F. Galdo; M.J. López-Armada; F.J. Blanco


Book ID
113732801
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
470 KB
Volume
16
Category
Article
ISSN
1063-4584

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The effects of IL-1 p and TGF-P on the biosynthesis of extracellular matrix structural components relative to the metalloproteinases and their inhibitor TlMPl in human articular chondrocytes were investigated. It has been proposed that TGFp, acting as a positive regulator of matrix accretion, can co