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Anti-amyloid activity of neprilysin in plaque-bearing mouse models of Alzheimer’s disease

✍ Scribed by M.Hasan Mohajeri; Katrin Kuehnle; Hong Li; Raphael Poirier; Jay Tracy; Roger M. Nitsch


Book ID
117106325
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
483 KB
Volume
562
Category
Article
ISSN
0014-5793

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## Abstract We performed three‐dimensional, high‐resolution magnetic resonance imaging (MRI) of fixed mouse brains to determine whether MRI can detect amyloid plaques in transgenic mouse models of Alzheimer's disease. Plaque‐like structures in the cortex and hippocampus could be clearly identified