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Anti-aggregant effects on human platelets of the crude aqueous extract and polar fractions of the microalga Dunaliella tertiolecta

✍ Scribed by Rosa Villar; Reyes Laguna; Dorotea Martínez; Lucía Núñez; Carlos Jiménez

Publisher: John Wiley and Sons
Year: 1997
Tongue: English
Weight: 102 KB
Volume: 11
Category: Article
ISSN: 0951-418X
DOI: 10.1002/(sici)1099-1573(199702)11:1<70::aid-ptr36>3.0.co;2-u

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✦ Synopsis

The crude aqueous extract of the microalga Dunaliella tertiolecta was found to have strong inhibitory effects on the aggregation of human platelets induced by thrombin, arachidonic acid and ionomycin. The extraction of the crude aqueous extract with i PrOH and posterior fractionation with solvents of increasing polarity, concentrated the activity in the more polar fractions.

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