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Anthracycline dose intensification in adult acute lymphoblastic leukemia : Lack of benefit in the context of the fractionated cyclophosphamide, vincristine, doxorubicin, and dexamethasone regimen

✍ Scribed by Deborah Thomas; Susan O'Brien; Stefan Faderl; Farhad Ravandi; Elias Jabbour; Sherry Pierce; Jorge Cortes; Hagop Kantarjian

Publisher: John Wiley and Sons
Year: 2010
Tongue: English
Weight: 186 KB
Volume: 116
Category: Article
ISSN: 0008-543X
DOI: 10.1002/cncr.25319

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vanced and/or progressive disease was defined by high Total Tumor Mass (TTM) score (ú9), and/or short doubling time (DT) (õ12 months), and/or bone marrow for the International Society for Chemo-Immunotherapy, Vienna failure. The response to therapy was defined by reduction of the initial TTM score.