✦ LIBER ✦
High dose chlorambucil versus Binet's modified cyclophosphamide, doxorubicin, vincristine, and prednisone regimen in the treatment of patients with advanced B-cell chronic lymphocytic leukemia : Results of an international multicenter randomized trial
✍ Scribed by Branimir Jaksic; Maura Brugiatelli; Ivo Krc; Hajna Losonczi; Jerzy Holowiecki; Ana Planinc-Peraica; Rajko Kusec; Fortunato Morabito; Pasquale Iacopino; Dieter Lutz
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 115 KB
- Volume
- 79
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
✦ Synopsis
vanced and/or progressive disease was defined by high Total Tumor Mass (TTM) score (ú9), and/or short doubling time (DT) (õ12 months), and/or bone marrow for the International Society for Chemo-Immunotherapy, Vienna failure. The response to therapy was defined by reduction of the initial TTM score.
The end points of the trial were response rate, survival, and toxicity.