Background. Anterior craniofacial resection is now recognized as the best treatment for ethmoid tumors involving the cribriform plate with or without invasion of anterior cranial fossa. Methods. Ninety-one patients underwent an anterior craniofacial resection for ethmoid malignant tumors at the Mil
Anterior craniofacial resection for malignant paranasal tumors: A monoinstitutional experience of 366 cases
โ Scribed by Giulio Cantu; Carlo L. Solero; Rosalba Miceli; Flavia Mattana; Stefano Riccio; Sarah Colombo; Madia Pompilio; Giuseppe Lombardo; Paolo Formillo; Pasquale Quattrone
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 278 KB
- Volume
- 34
- Category
- Article
- ISSN
- 1043-3074
No coin nor oath required. For personal study only.
โฆ Synopsis
Abstract
Background
The purpose of this study was to evaluate the results of a monoโinstitutional series of patients treated with anterior craniofacial resection for malignant paranasal sinus tumors.
Methods
We analyzed all patients with malignant paranasal sinus tumors treated with anterior craniofacial resection at our institution between 1987 and 2007. All tumors were classified according to both the American Joint Committee on Cancer (AJCC)โ2002 and the Istituto Nazionale Tumori (INT) classifications.
Results
The sample included 366 patients. There was intraorbital spread in 108 cases. The skull base was eroded in 127 patients, with dura or brain involvement in 93 patients. The 10โyear diseaseโspecific survival was 53.1%. Histologic subtype, INT stage, surgical margins, and postsurgical radiotherapy were significant, independent predictors for both local relapse and diseaseโspecific survival (DSS). The AJCCโ2002 classification was not significant when tested in place of INT stage.
Conclusion
Our data indicated that craniofacial resection and postsurgical radiotherapy remain the primary option for malignant tumors involving the anterior skull base. ยฉ 2011 Wiley Periodicals, Inc. Head Neck, 2012
๐ SIMILAR VOLUMES
Background. Malignant tumors of the superior sinonasal vault are rare, and, because of this and the varied histologic findings, most outcomes data reflect the experience of small patient cohorts. This International Collaborative study examines a large cohort of patients accumulated from multiple ins
## Background: The rarity of sinonasal tumors has precluded long-term follow-up of large series of craniofacial resections until now. ## Methods: A series of 209 patients suffering from a wide range of histologies who had undergone craniofacial resection for sinonasal neoplasia with up to 17 year
## Background: Craniofacial resection is the established "gold standard" for surgical treatment of tumors affecting the anterior skull base. ## Methods: This study analyzed 308 patients (220 males, 88 females) who had undergone craniofacial resection for sinonasal neoplasia with up to 25-year fol
## Abstract ## Objective/Hypothesis: Craniofacial resection (CFR) represents the traditional approach for resection of anterior skull base (ASB) malignancies. However, this past decade has witnessed the emergence of transnasal endoscopic ASB resection (TER) as a feasible alternative. The aim of th