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Antagonistic effects of dexamethasone and 1,25-dihydroxyvitamin D3 on the synthesis of nerve growth factor

✍ Scribed by Neveu, Isabelle; Barbot, Nelly; Jehan, Frédéric; Wion, Didier; Brachet, Philippe

Book ID
123242829
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
697 KB
Volume
78
Category
Article
ISSN
0303-7207

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✍ D. Wion; D. Macgrogan; I. Neveu; F. Jehan; R. Houlgatte; P. Brachet 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 563 KB

1,25-Dihydroxyvitamin D3 (1,25-(OH)2D3), a metabolically active form of vitamin D, is shown to increase in a dose-dependent manner the cellular pool of NGF mRNA in murine L-929 fibroblasts cultured in a serum-free medium. This effect can be detected as early as 3 hours after 1,25-(OH)2D3 addition an