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1,25-Dihydroxyvitamin D3 regulates the synthesis of nerve growth factor in primary cultures of glial cells

✍ Scribed by Isabelle Neveu; Philippe Naveilhan; Fre´de´ric Jehan; Christel Baudet; Didier Wion; Hector F. De Luca; Philippe Brachet


Book ID
119138869
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
985 KB
Volume
24
Category
Article
ISSN
0169-328X

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The vitamin D receptor (VDR) is a nuclear receptor that mediates the effect of the active metabolite of vitamin D3, the 1,25-dihydroxyvitamin D3 (1,25-(OH)2D3). To investigate the potential role of this hormone in the peripheral nervous system, we have studied the VDR expression in Schwann cells. Th