AnRBP4promoter polymorphism increases risk of type 2 diabetes
β Scribed by M. van Hoek; A. Dehghan; M. C. Zillikens; A. Hofman; J. C. Witteman; E. J. G. Sijbrands
- Publisher
- Springer
- Year
- 2008
- Tongue
- English
- Weight
- 157 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0012-186X
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π SIMILAR VOLUMES
## Aims/hypothesis Obesity is a major risk factor for type 2 diabetes. Recent genome-wide association (GWA) studies have identified multiple loci robustly associated with BMI and risk of obesity. However, information on their associations with type 2 diabetes is limited. Such information could help
Objectives (a) To study whether there was an increased prevalence of glucose intolerance in the parents of probands with Type 1 diabetes and (b) to look for any possible link between the glucose intolerance in the parents with HLA-DQB1 alleles transmitted in excess to the Type 1 diabetes offspring.