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Interaction of eNOS polymorphism with MTHFR variants increase the risk of diabetic nephropathy and its progression in type 2 diabetes mellitus patients

✍ Scribed by Yazdan Jafari; Zohreh Rahimi; Asad Vaisi-Raygani; Mansour Rezaei

Publisher
Springer
Year
2011
Tongue
English
Weight
224 KB
Volume
353
Category
Article
ISSN
0300-8177

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## Abstract ## Background Poor glycaemic control, hypertension and duration of diabetes are risk factors for the development of diabetic nephropathy, but there may be genetic factors. Recently, a common C to T mutation at nucleotide position 677 of the MTHFR gene (MTHFR677C > T) has been reported