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Anoxia-induced changes in reactive oxygen species and cyclic nucleotides in the painted turtle

✍ Scribed by Matthew Edward Pamenter; Michael David Richards; Leslie Thomas Buck

Publisher: Springer-Verlag
Year: 2007
Tongue: English
Weight: 372 KB
Volume: 177
Category: Article
ISSN: 0174-1578
DOI: 10.1007/s00360-007-0145-8

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## Abstract Microglia are activated by lipopolysaccharide (LPS) to produce neurotoxic pro‐inflammatory factors and reactive oxygen species (ROS). While a multitude of LPS receptors and corresponding pathways have been identified, the detailed mechanisms mediating the microglial response to LPS are