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Another pedigree with familial acute myeloid leukemia and germline CEBPA mutation

✍ Scribed by Renneville, A; Mialou, V; Philippe, N; Kagialis-Girard, S; Biggio, V; Zabot, M-T; Thomas, X; Bertrand, Y; Preudhomme, C


Book ID
109886660
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
167 KB
Volume
23
Category
Article
ISSN
0887-6924

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## Abstract To assess the prevalence of mutations in the __CEBPA__ gene, which encodes the myeloid transcription factor CEBPA in specific cytogenetic subgroups, we initially studied 125 patients with acute myeloid leukemia (AML). Five of the eight patients with del(9q) as the sole aberration or in