## Abstract The __AML1__ gene (also known as __RUNX1__) at 21q22 codes for core binding factor (CBF) ฮฑ, which forms a heterodimer with CBF ฮฒ that acts as a transcriptional activating factor. CBF is a critical regulator in the generation and differentiation of definitive hematopoietic stem cells and
Hereditary thrombocytopenia and acute myeloid leukemia: a common link due to a germline mutation in the AML1 gene
โ Scribed by Iris Appelmann; Tobias Linden; Annika Rudat; Carsten Mueller-Tidow; Wolfgang E. Berdel; Rolf M. Mesters
- Publisher
- Springer
- Year
- 2009
- Tongue
- English
- Weight
- 63 KB
- Volume
- 88
- Category
- Article
- ISSN
- 0939-5555
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