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Anodic Cyanation of (-)-N-Phenyl-2-methylpiperidine: A Short Synthesis of (+)-Solenopsin A and (+)-Isosolenopsin A.

โœ Scribed by Nicolas Girard; Jean-Pierre Hurvois; Loic Toupet; Claude Moinet


Publisher
John Wiley and Sons
Year
2005
Weight
23 KB
Volume
36
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Reductive Cyanation
โœ J.-O. DURAND; M. LARCHEVEQUE; Y. PETIT ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 30 KB ๐Ÿ‘ 1 views

Reductive Cyanation: A Key Step for a Short Synthesis of (-)-(2S,3S)-3-Hydroxyproline. -A short, stereoselective synthesis of a 3-hydroxyproline (VII) starting from L-malic acid is described. Key step is a stereospecific reductive cyanation of compound (IV), which leads in contrast to former studie