The physical stability of active pharmaceutical ingredients (APIs) formulated in the crystalline state may be compromised in the presence of excipients. In the present study, it is shown that at high relative humidity, several model crystalline drugs compacted into a matrix of poly(ethylene oxide) (
Anisotropy of motion in solutions of poly(ethylene oxide) in the presence of the crystalline phase
✍ Scribed by D. Doskočilová; B. Schneider; Z. Pelzbauer; J. Zajl'ček
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- English
- Weight
- 560 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0032-3861
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
The polymer-polymer interaction potential used in an earlier reported MD simulation of crystalline PEO [Neyertz, Brown and Thomas, J. Chem. Phys., 101, 10064 (1994)] is here transferred to the crystalline phase of poly(ethylene oxide)-sodium iodide, PEO,NaI. An appropriate set of ion-ion and ion-po
Several types of copolymers containing poly(ethylene oxide) (PEO) combined with polybuladiene, polystyrene, poly(ethyl acrylate), poly(butyl acrylate), propylene oxide or allyl glycolyl ether were investigated by wide angle X-ray scattering (WAXS). Two kinds of crystallinities, apparent and substant