✦ LIBER ✦

Anisochrony of isopropyl methyl groups in 1-isopropyl-substituted tetralins and indans

✍ Scribed by N. Pourahmady; V. A. Palaniswamy; E. J. Eisenbraun

Publisher: John Wiley and Sons
Year: 1983
Tongue: English
Weight: 200 KB
Volume: 21
Category: Article
ISSN: 0749-1581
DOI: 10.1002/omr.1270211106

No coin nor oath required. For personal study only.

✦ Synopsis

l-Isopropyl-5-methylindan, l-isopropyl-7-methyIindm and l-isopropyl-1,2,3,4-tebrahymonaphthalene show a large anisochrony (magnetic non-equivalence) of the isopropyl methyl signals at room temperature in their ' I 3 NMR specha. A decrease in magnitude of this anisochrony is observed, in each case, in the temperature range 30-150°C. However, for l-isopropyI-8-methylteb.alin, the magnitude of the non-equivalence of the isopropyl methyl signals is unexpectedly small. These latter signals converge at 85 "C and then diverge in the opposite direction over the range 85-150 "C. This alteration in anisochrony with temperature change for all cases is observed as a continuous d o d e l d migration of one signal which, in turn, results from variations in conformation populations. We thank Oklahoma State University for support through a Presidential Challenge Grant and the US Department of Energy, Bartlesville Energy Technology Center, for support through contract DE-~. ~~ 1,2,4-trichlorobenzene. TMS was used as a reference AS19-80BCri0307.

📜 SIMILAR VOLUMES

Synthesis, β-Adrenergic Blocking Activit

Synthesis, β-Adrenergic Blocking Activity and β-Receptor Binding Affinities of 1-Substituted-3-(2-isopropyl-5-methyl-phenoxy)-propan-2-ol Oxalates.

✍ Dharam Paul Jindal; Mohane S. Coumar; K. Nandakumar; Subhash Laxmanrao Bodhankar 📂 Article 📅 2003 🏛 John Wiley and Sons ⚖ 76 KB 👁 1 views

The thermodynamics of dipeptides in wate

The thermodynamics of dipeptides in water. Part IV. Calorimetric study of the influence of methyl and isopropyl chains on the free α-carboxyl and free α-amino groups

✍ F. Rodante; F. Fantauzzi; V. Mucciante 📂 Article 📅 1996 🏛 Elsevier Science 🌐 English ⚖ 662 KB

ChemInform Abstract: Discovery and Precl

ChemInform Abstract: Discovery and Preclinical Studies of 5-Isopropyl-6-(5-methyl-1,3,4-oxadiazol-2-yl)-N-(2-methyl-1H-pyrrolo [2,3-b]pyridin-5-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine (BMS-645737), an in vivo Active Potent VEGFR-2 Inhibitor.

✍ Rejean Ruel; et al. et al. 📂 Article 📅 2008 🏛 John Wiley and Sons ⚖ 20 KB 👁 2 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v

Nitropyrazoles. Part 11. Isomeric 1-Meth

Nitropyrazoles. Part 11. Isomeric 1-Methyl-3(5)-nitropyrazole-4-carbonitriles in Nucleophilic Substitution Reactions. Comparative Reactivity of the Nitro Group in Positions 3 and 5 of the Pyrazole Ring.

✍ I. L. Dalinger; A. A. Zaitsev; T. K. Shkineva; S. A. Shevelev 📂 Article 📅 2005 🏛 John Wiley and Sons ⚖ 150 KB 👁 1 views