The conformational quality of insoluble
✍
Andrea Vera; Nuria González-Montalbán; Anna Arís; Antonio Villaverde
📂
Article
📅
2007
🏛
John Wiley and Sons
🌐
English
⚖ 178 KB
👁 1 views
## Abstract Protein aggregation is a major bottleneck during the bacterial production of recombinant proteins. In general, the induction of gene expression at sub‐optimal growth temperatures improves the solubility of aggregation‐prone polypeptides and minimizes inclusion body (IB) formation. Howev