𝔖 Bobbio Scriptorium
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AnIn Vitrostrategy for the rapid expression of recombinant proteins at low temperatures

✍ Scribed by Ju-Young Byun; Dong-Myung Kim


Book ID
107637857
Publisher
The Korean Society for Biotechnology and Bioengineering
Year
2008
Tongue
English
Weight
256 KB
Volume
13
Category
Article
ISSN
1226-8372

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## Abstract Protein aggregation is a major bottleneck during the bacterial production of recombinant proteins. In general, the induction of gene expression at sub‐optimal growth temperatures improves the solubility of aggregation‐prone polypeptides and minimizes inclusion body (IB) formation. Howev