Animal models of the cancer anorexia–cachexia syndrome
✍ Scribed by Nabila Bennani-Baiti; Declan Walsh
- Publisher
- Springer-Verlag
- Year
- 2010
- Tongue
- English
- Weight
- 255 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0941-4355
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## BACKGROUND. Imbalanced amino acid diets in animals rapidly produce anorexia and weight loss. Blockade of type 3 serotonergic receptors (5HT 3 ) can ameliorate anorexia in this animal model. Imbalanced plasma amino acid levels also have been documented in both animal models and human patients wit
## Abstract Prostate cancer (CaP) patients with disseminated disease often suffer from severe cachexia, which contributes to mortality in advanced cancer. Human cachexia‐associated protein (HCAP) was recently identified from a breast cancer library based on the available 20‐amino acid sequence of p