✦ LIBER ✦

Animal models for wound repair

✍ Scribed by Davidson, J. M.

Book ID: 120233180
Publisher: Springer-Verlag
Year: 1998
Tongue: English
Weight: 108 KB
Volume: 290
Category: Article
ISSN: 0340-3696
DOI: 10.1007/PL00007448

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Progress in wound pharmacology is dependent on the availability of suitable animal wound models. All animal models try to reflect human wound healing problems. In acute models it is easier to achieve approximations to the clinical situation than in models for the chronic wound.

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Wound healing in adult mammals proceeds by a series of overlapping highly coordinated events. Dermal wound repair commences with the arrest of hemorrhage followed by an inflammatory response, re-epithelialization of the wound, and formation of granulation tissue within the wound space, culminating i