Animal and human models for studying effects of drugs on intestinal fluid transport in vivo
โ Scribed by Fadi H. Mourad
- Book ID
- 113941010
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 311 KB
- Volume
- 50
- Category
- Article
- ISSN
- 1056-8719
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The intestinal efflux pump, P-glycoprotein (P-gp), located in the apical membranes of intestinal absorptive cells, can reduce the bioavailability of a wide range of drugs which are substrates for this membrane transporter. In addition to anticancer and anti-HIV drugs, NCEs for other disease indicati
A new generation drug delivery system, named the Microsealed Drug Delivery (MDD) system, was developed. Subcutaneous implantation of MDD's in rats for up to 129 days resulted in a constant release profile of desoxycorticosterone acetate. Three formulations were examined. An excellent i n uitro-in ui