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Angiotensin II induces vascular endothelial growth factor synthesis in mesenchymal stem cells

โœ Scribed by Rui-Zhen Shi; Ji-Chang Wang; Song-Hua Huang; Xiao-Jun Wang; Qing-Ping Li


Book ID
113955810
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
497 KB
Volume
315
Category
Article
ISSN
0014-4827

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Vascular endothelial growth factor (VECF) is a 45kDa secreted peptide that has potent mitogenic activity specific for endothelial cells in vitro and the ability to induce a strong angiogenic response in vivo. In the present study, 24 h treatment with VEGF resulted in a stimulation of expression of t