## Abstract We previously showed that prolonged and strong ERK phosphorylation induced by Compound 5 (Cpd 5), a Cdc25A protein phosphatase inhibitor, was involved in its mechanism of cell growth inhibition. To study the relationship between ERK phosphorylation and cell growth inhibition, we used Cp
Angiotensin II induces endothelial cell senescence via the activation of mitogen-activated protein kinases
β Scribed by HaiYan Shan; XiaoJuan Bai; XiangMei Chen
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 209 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0263-6484
- DOI
- 10.1002/cbf.1467
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Using spontaneously hypertensive and aortic banded rats, we have shown that expression of myocardial osteopontin, an extracellular matrix protein, coincides with the development of heart failure and is inhibited by captopril, suggesting a role for angiotensin II (ANG II). This study tes
## Abstract Garlic has been used for prevention and treatment of hypertension; however, the molecular mechanisms of garlic's effects remain to be elucidated. In this study, the mechanisms of the __in vitro__ effect of organosulphur compounds derived from garlic on growth and migration of cultured a
## Abstract Angiotensin II (Ang II) induces, through AT1, intracellular Ca^2+^ increase in both normal and cancerous breast cells in primary culture (Greco et al., 2002 Cell Calcium 2:1β10). We here show that Ang II stimulated, in a doseβdependent manner, the 24 hβproliferation of breast cancer cel
## HIV induces activation of phosphatidylinositol 4-kinase and mitogen-activated protein kinase by interacting with T cell CD4 surface molecules T cell surface CD4 molecules act as co-receptors that amplify the T cell receptor (TcR)/CD3-induced signal transduction by a mechanism that requires the
The biliary epithelium is exposed to mediators of inflammation such as bacterial endotoxin or lipopolysaccharide (LPS) in a variety of inflammatory conditions. These conditions are also characterized by cholangiocyte proliferation and a predisposition to malignancy. Furthermore, LPS can enhance the