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Angiopoietin-like proteins stimulate ex vivo expansion of hematopoietic stem cells

✍ Scribed by Zhang, Cheng Cheng; Kaba, Megan; Ge, Guangtao; Xie, Kathleen; Tong, Wei; Hug, Christopher; Lodish, Harvey F

Book ID
109932798
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
376 KB
Volume
12
Category
Article
ISSN
1078-8956

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Background Extensive efforts to develop hematopoietic stem cell (HSC) based gene therapy have been hampered by low gene marking. Major emphasis has so far been directed at improving gene transfer efficiency, but low gene marking in transplanted recipients might equally well reflect compromised repop