Optimization of ex vivo hematopoietic stem cell expansion in intermittent dynamic cultures
β Scribed by Yong-Soo Choi; Sang-Eun Noh; Sang-Min Lim; Dong-il Kim
- Publisher
- Springer Netherlands
- Year
- 2010
- Tongue
- English
- Weight
- 467 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0141-5492
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Background Extensive efforts to develop hematopoietic stem cell (HSC) based gene therapy have been hampered by low gene marking. Major emphasis has so far been directed at improving gene transfer efficiency, but low gene marking in transplanted recipients might equally well reflect compromised repop
## Abstract Since umbilical cord blood (UCB), contains a limited hematopoietic stem/progenitor cells (HSC) number, successful expansion protocols are needed to overcome the hurdles associated with inadequate numbers of HSC collected for transplantation. UCB cultures were performed using a human str