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Angiogenesis Modulations in Health and Disease: Practical Applications of Pro- and Anti-angiogenesis Targets

✍ Scribed by Shaker A. Mousa, Paul J. Davis (auth.), Shaker A. Mousa, Paul J. Davis (eds.)


Publisher
Springer Netherlands
Year
2013
Tongue
English
Leaves
209
Edition
1
Category
Library

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✦ Synopsis


This book is a major update of novel targets in angiogenesis modulation, including pro- and anti-angiogenesis. There is in-depth coverage of preclinical and clinical methods and models, investigational status, and clinical applications. The impact of nanotechnology in advancing the applications of pro-and anti-angiogenesis strategies is also highlighted, along with stem cell and biotechnologies in research and development of angiogenesis modulating targets.

✦ Table of Contents


Front Matter....Pages i-x
Angiogenesis Assays: An Appraisal of Current Techniques....Pages 1-12
Front Matter....Pages 13-13
Survey of Pro-angiogenesis Strategies....Pages 15-18
Angiogenesis Modulation by Arachidonic Acid-derived Lipids: Positive and Negative Regulators of Angiogenesis....Pages 19-28
Pro-angiogenic Activity of Thyroid Hormone Analogues: Mechanisms, Physiology and Clinical Prospects....Pages 29-46
Actions of Steroids and Peptide Hormones on Angiogenesis....Pages 47-53
Role of Non-neuronal Nicotinic Acetylcholine Receptors in Angiogenesis Modulation....Pages 55-75
Catecholamine Neurotransmitters: An Angiogenic Switch in the Tumor Microenvironment....Pages 77-86
Impact of Nanotechnology on Therapeutic Angiogenesis....Pages 87-92
Front Matter....Pages 93-93
Survey of Anti-angiogenesis Strategies....Pages 95-106
Tetraiodothyroacetic Acid (Tetrac), Nanotetrac and Anti-angiogenesis....Pages 107-117
Integrin Antagonists and Angiogenesis....Pages 119-141
Anti-angiogenesis Therapy as an Adjunct to Chemotherapy in Oncology....Pages 143-155
Anti-VEGF Strategies in Ocular Angiogenesis-mediated Disorders, with Special Emphasis on Age-related Macular Degeneration....Pages 157-172
Application of Nanotechnology to Prevent Tumor Angiogenesis for Therapeutic Benefit....Pages 173-180
Biomarkers of Response and Resistance to Anti-angiogenic Treatment....Pages 181-198
Speculations on New Directions in Which Angiogenesis May Proceed....Pages 199-203
Back Matter....Pages 205-206

✦ Subjects


Biomedicine general; Neurosciences; Pharmacy; Life Sciences, general; Biotechnology; Cell Biology


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