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Anencephaly and faciocranioschisis: Evidence of complete failure of closure 3 of the neural tube in humans

✍ Scribed by Urioste, Miguel; Rosa, Alejandro


Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
13 KB
Volume
75
Category
Article
ISSN
0148-7299

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✦ Synopsis


We report on a patient with median cleft of face and anencephaly as apparent consequence of delayed closure of the most rostral end of the neural tube. No other structural anomalies were found. To our knowledge, this child represents the first description of an isolated and complete failure of closure 3 of the neural tube and supports the hypothesis of a multi-site model of neural tube closure in humans.


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