𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Androgen receptor polyglutamine repeat number: models of selection and disease susceptibility

✍ Scribed by Calen P. Ryan; Bernard J. Crespi

Book ID
114901800
Publisher
Wiley (Blackwell Publishing)
Year
2012
Tongue
English
Weight
162 KB
Volume
6
Category
Article
ISSN
1752-4563

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

B2 attenuates polyglutamine-expanded and
B2 attenuates polyglutamine-expanded androgen receptor toxicity in cell and fly models of spinal and bulbar muscular atrophy
✍ Isabella Palazzolo; Natalia B. Nedelsky; Caitlin E. Askew; George G. Harmison; A πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 367 KB

## Abstract Expanded polyglutamine tracts cause neurodegeneration through a toxic gain‐of‐function mechanism. Generation of inclusions is a common feature of polyglutamine diseases and other protein misfolding disorders. Inclusion formation is likely to be a defensive response of the cell to the pr