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Androgen receptor levels are increased by interferons in human prostate stromal and epithelial cells

✍ Scribed by Basrawala, Z; Alimirah, F; Xin, H; Mohideen, N; Campbell, S C; Flanigan, R C; Choubey, D


Book ID
110070327
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
202 KB
Volume
25
Category
Article
ISSN
0950-9232

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Androgen receptors are expressed at a low level in the cell line PC-3, which does not respond to either androgens or antiandrogens. If these cells are exposed to natural beta-interferon (beta-IFN) a reduction in cell growth and an increase in androgen receptors, evaluated by both biochemical and imm