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Androgen receptor amplification is associated with increased cell proliferation in prostate cancer

✍ Scribed by Kyllikki Haapala; Tuula Kuukasjärvi; Eija Hyytinen; Immo Rantala; Heikki J. Helin; Pasi A. Koivisto


Book ID
116534284
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
477 KB
Volume
38
Category
Article
ISSN
1532-8392

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p53 protein expression of 30 hormone-refractory locally recurrent prostate cancers was compared with their matched untreated primary tumour specimens. In addition, androgen receptor (AR) gene amplification and p53 protein immunostaining were compared. p53 positivity increased during hormonal therapy