(+)- and (−)-Mutisianthol: First Total Synthesis, Absolute Configuration, and Antitumor Activity †
✍ Scribed by Bianco, Graziela G.; Ferraz, Helena M. C.; Costa, Arinice M.; Costa-Lotufo, Letícia V.; Pessoa, Cláudia; de Moraes, Manoel O.; Schrems, Marcus G.; Pfaltz, Andreas; Silva, Luiz F.
- Book ID
- 118742245
- Publisher
- American Chemical Society
- Year
- 2009
- Tongue
- English
- Weight
- 245 KB
- Volume
- 74
- Category
- Article
- ISSN
- 0022-3263
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Asymmetric synthesis of putaminoxin, a phytotoxic macrolide from the cultured dinoflagellate Amphidinium sp., has been accomplished. Absolute configuration of putaminoxin was concluded to be 1 from comparison of the NMR data and [a] D values of synthetic and natural putaminoxin.