and 7-chlorocavernicolenone, two new metabolites of the mediterranean sponge Aplysina (= Verongia) cavernicola
✍ Scribed by D'Ambrosio, Michele; Guerriero, Antonio; Pietra, Francesco
- Book ID
- 123431414
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- English
- Weight
- 270 KB
- Volume
- 83
- Category
- Article
- ISSN
- 1096-4959
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## Abstract A novel, mildly antibacterial, α‐bromoenone (7‐bromocavernicolenone) has been isolated from the Mediterranean sponge __Aplysina__ (= __Verongia__) __cavernicola__. Its structure, 7‐bromo‐1,5‐dihydroxy‐2‐azabicyclo[3.3.1]non‐6‐en‐3,8‐dione (**3**), is based on X‐ray and NMR analysis and
## Abstract Butanolic extracts of the Mediterranean sponge __Aplysina__ (= __Verongia__) __cavernicola__ have given, by reverse‐phase HPLC, the antibacterial quinols (±)‐3‐bromoverongiaquinol (= (±)‐3‐bromo‐1‐hydroxy‐4‐oxo‐2,5‐cyclohexadine‐1‐acetamide; **1d)** and (±)‐3‐bromo‐5‐chloroverongiaquino