Anatomy of the Hypophysiotropic Somatostatinergic and Growth Hormone-releasing Hormone System Minireview
✍ Scribed by Mariann Fodor; Claude Kordon; Jacques Epelbaum
- Book ID
- 106483366
- Publisher
- Springer
- Year
- 2006
- Tongue
- English
- Weight
- 196 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0364-3190
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## Abstract Internalization and intracellular trafficking of the growth hormone‐releasing hormone receptor (GHRH‐R) were studied in rat anterior pituitary and human (h) and rat (r) GHRH‐R‐transfected BHK cells, with the GHRH agonist, [N^α^‐5‐carboxyfluoresceinyl‐D‐Ala^2^, Ala^8^, Ala^15^, Lys^22^]h
The stability of a new active growth hormonereleasing hormone analogue (~-Ala\*,Nle", (gamma-amino-butyric acid)s-GHRH(1-30)-NH3 was investigated during storage at different temperatures in aqueous solution. Samples stored for various periods of time were analysed by HPLC. It is concluded that in aq