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Anandamide stimulates phospholipase D activity in PC12 cells but not in NIH 3T3 fibroblasts

โœ Scribed by Zoltan Kiss


Book ID
117110615
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
147 KB
Volume
447
Category
Article
ISSN
0014-5793

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Phospholipase D (PLD) is activated in mammalian cells in response to a variety of growth factors and may play a role in cell proliferation. Lysophosphatidic acid (LPA) is a bioactive metabolite potentially generated as a result of PLD activation. Two human prostate cancer cell lines, PC-3 and LNCaP,