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Analytical control of the biological oxidation in the production of Δ1,4-androstadiene-3,17-dione

✍ Scribed by Mizsei, Antal ;Szabó, Antal


Publisher
Wiley (John Wiley & Sons)
Year
1960
Weight
261 KB
Volume
2
Category
Article
ISSN
0368-1467

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✦ Synopsis


Abstract

A rapid method for the assay of Δ^1,4^‐androstadiene‐3, 17‐dione has been worked out for use in the control of its production by biological oxidation. The method consists of a single selective extraction step, a specific colour reaction and a photometric measurement. Based upon the analyses of samples taken at frequent intervals, the oxidative process can be stopped at its optimum production level. Thus insufficient transformation and over‐oxidation can both be avoided. The time needed for one analysis is 20 minutes.


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