Analytical control of the biological oxidation in the production of Δ1,4-androstadiene-3,17-dione
✍ Scribed by Mizsei, Antal ;Szabó, Antal
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1960
- Weight
- 261 KB
- Volume
- 2
- Category
- Article
- ISSN
- 0368-1467
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✦ Synopsis
Abstract
A rapid method for the assay of Δ^1,4^‐androstadiene‐3, 17‐dione has been worked out for use in the control of its production by biological oxidation. The method consists of a single selective extraction step, a specific colour reaction and a photometric measurement. Based upon the analyses of samples taken at frequent intervals, the oxidative process can be stopped at its optimum production level. Thus insufficient transformation and over‐oxidation can both be avoided. The time needed for one analysis is 20 minutes.
📜 SIMILAR VOLUMES
Cycloaddition of PTAD to 7-methylenenorbornene (1 a) afforded the rearrangement urazole 2a, but not with 7-(pheny1methylene)norbornene (1 b) and 7-(chloromethylene)norbornene (lc). Instead, besides the [2 + 23 cycloadducts 3b and 3c, respectively, l b gave the double [4 + 23 adduct 4b and l c the no