## Modified liquid junction interface for nonaqueous capillary electrophoresis-mass spectrometry Electrospray ionization (ESI) is the most widely used ionization method in on-line coupling of capillary electrophoresis-mass spectrometry (CE-MS). The conventional coaxial sheath flow electrospray int
Analyte transport in liquid junction nano-electrospray interface between capillary electrophoresis and mass spectrometry
✍ Scribed by Karel Klepárník; Marek Otevřel
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 289 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0173-0835
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A Fisons Quattro I electrospray ionization (ESI) source has been modified to produce stable electrospray ion currents at flow rates as low as 50 nL/min. The original counter electrode and skimmer cone lens of the Fisons ESI source have been replaced with a spherical cone lens. This improved source p
On-line capillary zone electrophoresis/electrospray ionization mass spectrometry (CZE-ESMS) and capillary isoelectric focusing/electrospray ionization mass spectrometry (CIEF/ESMS) were employed for protein analysis. The separation mechanisms and the detection limits of CZE/ESMS and CIEF/ESMS were c