Analysis of tyrosine- and methionine-containing neuropeptides by fast atom bombardment mass spectrometry
โ Scribed by Jerzy Silberring; Fred Nyberg
- Book ID
- 103803990
- Publisher
- Elsevier Science
- Year
- 1991
- Weight
- 335 KB
- Volume
- 562
- Category
- Article
- ISSN
- 0378-4347
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Treatment of peptides containing methionine and/or tryptophan with dimethylsuifoxide/hydrochloric acidlacetic acid resulted in oxidation of these amino acids respectively to methionine sulfoxide and oxyindolalanine. This reaction was monitored by fast atom bombardment mass spectrometry using a dithi
Positive and negative ion FAB mass spectrometry were found to be useful for the structural analysis of phosphorylated peptides containing multiple O-phosphoseryl residues. The positive ion FAB mass spectra obtained for Ac-Ser(P)-Ser(P)-NHMe and Ac-Ser(P)-Ser(P)-Ser(P)-NHMe showed that [3-eliminative