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Analysis of the tumor suppressor gene p53 in xeroderma pigmentosum fibroblasts

✍ Scribed by Lavu, Sukadev; Srivastava, Meera; Srivastava, Shiv K.


Book ID
122664742
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
419 KB
Volume
85
Category
Article
ISSN
0304-3835

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Transgenic mice deficient for the p53 gene were reported to frequently develop angiosarcoma (AS), suggesting that alterations in the gene are associated with tumorigenesis of AS. However, little is known about genetic changes, including p53 gene alterations, in human AS because of its rarity. We ana